Status:

RECRUITING

Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years

Lead Sponsor:

Kaiser Permanente

Collaborating Sponsors:

Seqirus

Conditions:

Influenza

Community-acquired Pneumonia

Eligibility:

All Genders

65+ years

Brief Summary

This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in pr...

Eligibility Criteria

Inclusion

  • Age ≥65 years at the time of influenza vaccination
  • KPNC member at the time of vaccination
  • Receive either aIIV4 or HD-IIV4 at a KPNC facility during the 2023/24 and/or 2024/25 influenza seasons

Exclusion

  • Age \<65 years at the time of influenza vaccination
  • Received either aIIV4 or HD-IIV4 in the inpatient setting
  • Receive more than one influenza vaccination during a single season period (i.e., 2023/24 or 2024/25 influenza seasons)
  • Receive an influenza vaccination outside of KPNC

Key Trial Info

Start Date :

August 17 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2026

Estimated Enrollment :

960000 Patients enrolled

Trial Details

Trial ID

NCT06029933

Start Date

August 17 2023

End Date

May 1 2026

Last Update

September 8 2023

Active Locations (1)

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1

Kaiser Permanente Northern California (entire region)

Oakland, California, United States, 94612