Status:

COMPLETED

Stroke and CPAP Outcome Study 3

Lead Sponsor:

University of Washington

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Ischemic Stroke

Intra Cerebral Hemorrhage

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

A problem with breathing during sleep, called obstructive sleep apnea (OSA), likely increases the risk of stroke and is common in people who have had a stroke, present in about 2/3 of stroke survivors...

Detailed Description

In an initial single-arm study, participants with stroke will be tested for OSA and treated with auto-titrating CPAP during inpatient stroke rehabilitation and continued for a 3-month treatment period...

Eligibility Criteria

Inclusion

  • Age 18 years or older
  • Head CT or brain MRI demonstrating an acute ischemic infarction or intraparenchymal hemorrhage within past 30 days
  • Person providing consent (patient or legally authorized representative) able to be consented in English or Spanish

Exclusion

  • Unable to obtain informed consent from participant or surrogate
  • Incarcerated
  • Known pregnancy
  • Current mechanical ventilation, tracheostomy or supplemental oxygen use \> 4L/min
  • Current use of positive airway pressure or use within 14 days prior to stroke
  • History of pneumothorax, bullous emphysema or other serious co-morbid conditions which limit CPAP use
  • Stroke related to tumors, vascular malformations or subarachnoid hemorrhage
  • Active use of sedative drugs that can interfere with testing for obstructive sleep apnea (OSA)
  • Anticipated inpatient rehabilitation length of stay \< 3 nights

Key Trial Info

Start Date :

October 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2025

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT06029959

Start Date

October 1 2023

End Date

January 1 2025

Last Update

October 8 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

University of Washington

Seattle, Washington, United States, 98122