Status:
COMPLETED
The Optimal Dose of Indomethacin Suppository for Preventing Post-ERCP Pancreatitis
Lead Sponsor:
The First Affiliated Hospital of Soochow University
Conditions:
Pancreatitis
Cholangiopancreatography, Endoscopic Retrograde
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is a single-center, randomized, single-blind, parallel controlled clinical study to explore the optimal dose of postoperative indomethacin suppository for the prevention of post-ERCP pancre...
Detailed Description
This is a single-centre, randomized, single-blind, parallel-controlled designed clinical study to explore the optimal dose of postoperative indomethacin suppository for the prevention of post-ERCP pan...
Eligibility Criteria
Inclusion
- According to the "Chinese ERCP Guidelines (2018 Edition)", patients with various biliary and pancreatic diseases who have indications for ERCP examination and treatment, who are at least 18 years old and have no contraindications, and who can tolerate the examination;
- Preoperative blood coagulation function, liver and kidney function indicators are in the normal range;
- The patients agreed to participate in this experiment, signed the informed consent form, and was approved by the hospital ethics committee.
Exclusion
- Contraindications to indomethacin and other NSAIDs: such as allergy to indomethacin, severe heart failure, active peptic ulcer/bleeding, perioperative period of coronary artery bypass surgery, etc.;
- There are severe cardiovascular and cerebrovascular diseases, respiratory insufficiency and coagulation dysfunction, etc., and cannot tolerate ERCP examination;
- Those who have recently used indomethacin and other non-steroidal anti-infective drugs;
- Pregnant or lactating women.
Key Trial Info
Start Date :
November 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2024
Estimated Enrollment :
192 Patients enrolled
Trial Details
Trial ID
NCT06031363
Start Date
November 1 2022
End Date
January 31 2024
Last Update
March 15 2024
Active Locations (1)
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1
The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China, 215006