Status:
RECRUITING
Timing of Endoscopy in Cirrhotic Patients with Acute Variceal Bleeding
Lead Sponsor:
General Hospital of Shenyang Military Region
Conditions:
Acute Upper Gastrointestinal Bleeding
Acute Variceal Bleeding
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Endoscopy is important for the diagnosis and treatment of acute upper gastrointestinal bleeding (AUGIB), especially acute variceal bleeding (AVB), in patients with liver cirrhosis. However, the optima...
Detailed Description
A total of 368 cirrhotic patients presenting with AUGIB that is highly suspected to be from AVB will be enrolled. They will be stratified according to the severity of liver function and hemodynamic st...
Eligibility Criteria
Inclusion
- patients with AUGIB which is highly suspected to be caused by gastroesophageal variceal rupture;
- patients with a diagnosis of liver cirrhosis based on imaging and pathology;
- patients and/or their relatives who sign informed consents;
- patients' age ≥18 years.
Exclusion
- patients who have undergone endoscopy at other hospitals before admissions;
- patients' hemodynamics are unstable after resuscitation;
- patients with severe cardiovascular or cerebrovascular diseases or renal injury;
- patients who have taken anticoagulants or antiplatelet drugs within 2 weeks before admissions, or are diagnosed with severe hematological diseases;
- patients with human immunodeficiency virus or other acquired or congenital immune deficiency diseases;
- patients with mental illness;
- pregnancy.
Key Trial Info
Start Date :
September 4 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
368 Patients enrolled
Trial Details
Trial ID
NCT06031402
Start Date
September 4 2024
End Date
December 1 2026
Last Update
February 27 2025
Active Locations (1)
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1
Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area)
Shenyang, Liaoning, China