Status:

UNKNOWN

A Multimodal Intervention Program to Improve Sexual Health and Self-perceived Quality of Life in Patients Treated for Cervical Cancer (PROVIDENCE)

Lead Sponsor:

Hospital Clinic of Barcelona

Collaborating Sponsors:

Hospital Universitario 12 de Octubre

Conditions:

Cervical Cancer

Sexual Dysfunction

Eligibility:

FEMALE

18+ years

Phase:

PHASE4

Brief Summary

The PROVIDENCE Trial aims to explore the improvement of sexual health and self-perceived health related quality of life (measured by Patient Reported Outcome Measures) through a multimodal interventio...

Detailed Description

Cervical cancer treatment, both radical hysterectomy and chemoradiotherapy, can impair all scopes of daily life and, beyond the physical changes caused by treatment, has psychological and social impli...

Eligibility Criteria

Inclusion

  • Women older that 18 years, with initial or locally advanced primary cervical cancer
  • Squamous, adenocarcinoma or adenosquamous histology
  • Stage I-III cervical cancer treated with surgery and/or radiotherapy ± systemic treatment in - Gynecology Oncology Units of referral hospitals in Spain
  • Signed informed consent by the patient or legal guardian

Exclusion

  • Women younger tan 18 years
  • Pregnancy or breastfeeding
  • Patients with intraepithelial lesions of cervix uteri without invasive disease
  • Metastatic tumor in the cervix uteri or primary tumor with atypical histology
  • Inability to complete the questionnaires included in the study protocol
  • Contraindications for the use of topical vaginal estrogens
  • Patients undergoing fertility-preservation treatment (conization or trachelectomy)
  • Patients undergoing palliative treatment

Key Trial Info

Start Date :

January 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2025

Estimated Enrollment :

122 Patients enrolled

Trial Details

Trial ID

NCT06031493

Start Date

January 1 2025

End Date

April 1 2025

Last Update

February 28 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Hospital Clínic de Barcelona

Barcelona, Spain, 08036

2

Hospital Universitario 12 de Octubre

Madrid, Spain, 28041