Status:

NOT_YET_RECRUITING

Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment

Lead Sponsor:

First Affiliated Hospital, Sun Yat-Sen University

Conditions:

Renal Cell Carcinoma

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Whether patients with stage III clear cell renal cell carcinoma (ccRCC) should receive adjuvant targeted therapy or not is still on debate. The investigators invented a multimodal recurrence scoring s...

Eligibility Criteria

Inclusion

  • The informed consent has been obtained from the patient.
  • With confirmed diagnosis of stage III clear cell renal cell carcinoma
  • With moderate/good Eastern Cooperative Oncology Group (ECOG) health rating (PS): 0-1 score.
  • The patient receive no anti-cancer treatment before primary surgery.
  • The patient receive radical operation for renal cancer with negative margin.

Exclusion

  • Patients who have previously received neoadjuvant therapy
  • With severe comorbidities, such as cardiovascular disease, chronic obstructive pulmonary disease, diabetes mellitus, and chronic renal dysfunction.
  • With bad compliance or contraindication to enrollment.
  • Pregnant woman or lactating woman.
  • With contraindication to receive adjuvant targeted therapy.

Key Trial Info

Start Date :

October 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2033

Estimated Enrollment :

488 Patients enrolled

Trial Details

Trial ID

NCT06032728

Start Date

October 1 2023

End Date

October 1 2033

Last Update

September 13 2023

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