Status:
UNKNOWN
Intestinal Flora and Metabonomics of Appendicitis
Lead Sponsor:
HongyiQu
Conditions:
Appendicitis
Intestinal Metaplasia
Eligibility:
All Genders
1-14 years
Brief Summary
The goal of this observational study is to learn about the key bacterial flora and metabolites associated with appendicitis in children. The main questions it aims to answer are: * To screen out the ...
Detailed Description
Participants will detect feces using 16s ribosomal RiboNucleicAcid (16S rRNA) gene sequencing technology and differences of the fecal metabolites between healthy children and appendicitis children wer...
Eligibility Criteria
Inclusion
- Children aged 1-14 years who were initially diagnosed with appendicitis and underwent laparoscopic appendectomy
- Children aged 1-14 years with non-digestive tract disease and no history of digestive tract disease
Exclusion
- A family history of intestinal disease
- Allergic to antibiotic therapy drugs
- Patients with long-term drug use causing microbial structure changes or intestinal flora disorders
- Patients with other congenital diseases such as Meckel's diverticulum, intestinal rotation and other malrotation
- With other systemic diseases, such as obvious upper respiratory tract infection or myocarditis
- Children with other digestive system diseases after auxiliary examination or surgical diagnosis
Key Trial Info
Start Date :
April 3 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06035029
Start Date
April 3 2023
End Date
July 1 2025
Last Update
September 13 2023
Active Locations (1)
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1
The First Affiliated Hospital Of Shandong First Medcial Unversity
Jinan, Shandong, China, 0531