Status:

UNKNOWN

Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical Lesion

Lead Sponsor:

Istanbul Medipol University Hospital

Conditions:

Root Canal Infection

Periapical Diseases

Eligibility:

All Genders

18-65 years

Brief Summary

The goal of this observational study is to define the role of apical shaping and irrigation activation on root canal cleanliness. The main questions it aims to answer are: * does the effectiveness of...

Detailed Description

The aim of this study is to evaluate the effect of apical enlargement with two different diameters on the intraradicular microbiota of teeth with chronic apical periodontitis lesion before and after p...

Eligibility Criteria

Inclusion

  • Patients between the ages of 18-65
  • Patients complying with the ASA1 and ASA2 classification (American Society of Anesthesiology)
  • Patients who has molar teeth with radiolucent lesions in the periapical region
  • The volunteer himself/herself or his/her legal representative wants to participate in the research by signing the 'Voluntary Consent Form'.
  • Being able to tolerate the treatment physically and mentally

Exclusion

  • Patients who have taken antibiotics/corticosteroids in the last 3 months
  • Patients with systemic disease
  • Teeth that cannot be properly isolated with a rubber dam
  • Teeth without coronal sealing,
  • Teeth with periodontal pocket depth\>4 mm and teeth with crown / root fracture.
  • Individuals who continue or are considering starting orthodontic treatment during the research
  • Pregnant and lactating individuals
  • The volunteer himself/herself or his/her legal representative does not want to participate in the research by signing the 'Voluntary Consent Form'.
  • Teeth that are damaged enough to require post-core treatment.

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 30 2025

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT06035185

Start Date

December 1 2023

End Date

December 30 2025

Last Update

September 13 2023

Active Locations (1)

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Istanbul Medipol University School of Dentistry

Istanbul, Turkey (Türkiye), 34083