Status:
RECRUITING
AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy
Lead Sponsor:
Chinese Academy of Sciences
Collaborating Sponsors:
Peking University Cancer Hospital & Institute
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Conditions:
Gastric Cancer
Image
Eligibility:
All Genders
18+ years
Brief Summary
This study seeks to develop a deep-learning-based intelligent predictive model for the efficacy of neoadjuvant chemotherapy in gastric cancer patients. By utilizing the patients' CT imaging data, biop...
Detailed Description
This study seeks to develop a deep learning model to predict the outcomes of neoadjuvant chemotherapy in patients with gastric cancer. Leveraging participants' CT scans, biopsy pathology images, and c...
Eligibility Criteria
Inclusion
- Age 18 years or older;
- Pathologically diagnosed with advanced gastric cancer in accordance with the American AJCC's TNM staging standards;
- Have not undergone any systematic anti-cancer treatments before neoadjuvant chemotherapy and have not had surgery for local progression or distant metastasis;
- Received standard neoadjuvant chemotherapy as recommended by the clinical guidelines, and have documented treatment details;
- CT imaging and biopsy pathology images strictly taken within one month prior to starting neoadjuvant treatment;
- Patients possess comprehensive preoperative clinical information and post-operative TRG grading.
Exclusion
- Patients whose CT or pathology images are unclear, making lesion assessment infeasible;
- Patients diagnosed with other concurrent tumors.
Key Trial Info
Start Date :
September 10 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2029
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06035250
Start Date
September 10 2023
End Date
December 31 2029
Last Update
September 28 2023
Active Locations (22)
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1
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Beijing, China
2
Peking Union Medical College Hospital
Beijing, China
3
Peking University Cancer Hospital & Institute
Beijing, China
4
Peking University People's Hospital
Beijing, China