Status:

NOT_YET_RECRUITING

Can we Use a Simple Blood Test to Reduce Unnecessary Adverse Effects From Radiotherapy by Timely Identification of Radiotherapy-resistant Rectal Cancers? MeD-Seq Rectal Study

Lead Sponsor:

Erasmus Medical Center

Conditions:

Pathological Response Rate, Circulating Tumour DNA

Eligibility:

All Genders

18+ years

Brief Summary

Chemoradiation therapy (CRT) followed by surgery is currently the standard of care to treat patients with locally advanced rectal cancer (LARC). CRT reduces local recurrences, but is associated with s...

Eligibility Criteria

Inclusion

  • Age ≥18 years
  • Histologically confirmed rectal adenocarcinoma
  • Scheduled for neoadjuvant chemoradiation
  • Written informed consent.

Exclusion

  • Scheduled to another neoadjuvant schedule that comprises systemic chemotherapy or short-course radiation
  • Not able to read or understand Dutch language or mentally not capable.

Key Trial Info

Start Date :

October 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2027

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT06035471

Start Date

October 1 2023

End Date

June 1 2027

Last Update

September 13 2023

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