Status:
COMPLETED
Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papua
Lead Sponsor:
Syamsudin Abdillah,Ph.D, Pharm D
Collaborating Sponsors:
Dr Cipto Mangunkusumo General Hospital
PT Natura Nuswantara Nirmala
Conditions:
Malaria,Falciparum
Malaria, Vivax
Eligibility:
All Genders
15-60 years
Phase:
PHASE2
Brief Summary
Comparing the efficacy of the combination treatment of bitter melon fruit extract (Momordica charantia) with primaquine (MC+PQ) against the combination of dihydroartemisinin + piperaquine + primaquine...
Detailed Description
Every group therapy session was under team member supervision, required to complete follow-up visits on days 1, 2, 3, 5, 7, 14, 21, 28, 35, and 42. All of the studies 1 and 2 was split into more than ...
Eligibility Criteria
Inclusion
- incomplete therapy patients
- Age ≥15 years old male or female up to 60 years old.
- diagnosis and an outcome inspection microscopically suffering from Plasmodium falciparum malaria or Plasmodium vivax with density parasites 1000-100,000/µL
- History of fever within the past 24-48 hours with axillary temperature ≥ 37.5°C
- There were no signs of severe malaria
- had no chronic disease
- willing to follow up for 42 days; No consuming other antimalarial drugs within 2 weeks; willingly to participate in investigations and follow established procedures (informed consent)
Exclusion
- pregnant female, breastfeeding female, children and infants
- suffering a mental disturbance, heavy illness like kidney, liver, tuberculosis, cancer, AIDS and other heavy diseases
- one set of symptom or signs of severe malaria
- had a history of hypersensitivity, allergies, and antimalarial contraindications
- not willingly to follow the inquiry
Key Trial Info
Start Date :
January 11 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 16 2019
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06036030
Start Date
January 11 2019
End Date
April 16 2019
Last Update
September 13 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Manokwari Regional General Hospital
Manokwari, West Papua, Indonesia