Status:

RECRUITING

Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients With Psychosis

Lead Sponsor:

Centre Psychothérapique de Nancy

Conditions:

Psychosis

Schizophrenia

Eligibility:

All Genders

16-55 years

Phase:

NA

Brief Summary

This research concerns the study of language disorders of patients present in the spectrum of psychosis. It is indeed accepted that psychotic disorders are associated with language difficulties, which...

Eligibility Criteria

Inclusion

  • All Groups:
  • Patient affiliated or entitled to a social security scheme
  • Patient having received informed information on the study and having co-signed, with the investigator, a consent to participate in the study
  • For minor participants, at least one of the parents or holders of parental authority having been informed of the study, having received the information note relating to it and not having objected to the participation of his or her child
  • Native language: French
  • ARMS and FEP Patient Group:
  • Age between 16 and 35 years old
  • Present the criteria for EMRP or FEP as defined by the Comprehensive Assessment of At Risk Mental State (CAARMS) or present the criteria for Disorders of the course of thought to the items of the Schizophrenia Proneness Instrument (SPI-A)
  • Patients with schizophrenia group:
  • Age between 16 and 55 years old
  • Patient with diagnostic criteria for schizophrenia, as defined by DSM V (American Psychiatric Association, 2015)
  • Present the criteria for Disorganization of Speech and Formal Thought Disorder as defined by the Thinking, Language and Communication (TLC) Rating Scale.
  • Healthy Volunteers Group:
  • Age between 16 and 55 years old
  • Parental authorization (of both parents) to participate in the study for minor patients

Exclusion

  • All groups:
  • Pregnant, parturient or nursing mother
  • Person deprived of liberty by a judicial or administrative decision
  • Person in a life-threatening emergency
  • Adult subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
  • Adult person unable to express their consent and who is not the subject of a legal protection measure
  • Impairment of the subject making it difficult, if not impossible, for them to participate in the trial or to understand the information given to them
  • Abuse or dependence of any substance according to DSM V criteria excluding cannabis
  • Healthy Volunteers Group:
  • Evolving psychiatric pathology (axis I of the DSM IV, measured at the MINI) excluding anxiety disorder
  • Presence of developmental disorder of oral language or written language revealed on clinical examination.

Key Trial Info

Start Date :

January 23 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 23 2026

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06036316

Start Date

January 23 2024

End Date

January 23 2026

Last Update

February 13 2025

Active Locations (1)

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Centre Psychothérapeutique de Nancy

Laxou, France, France, 54520