Status:
RECRUITING
Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing
Lead Sponsor:
Air Force Military Medical University, China
Collaborating Sponsors:
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tang-Du Hospital
Conditions:
Cancer Diagnosis
LungCancer
Eligibility:
All Genders
20-80 years
Brief Summary
The goal of this observational study is to screen and differentiate common cancers in participants with or without suspicious lesions. The main question the investigators aim to answer is: Can the dev...
Eligibility Criteria
Inclusion
- \>20 and \< 80 years old.
- Cancer group: Newly diagnosed cancer patients with a confirmed pathological diagnosis within 90 days before blood collection or within 30 days after blood collection, including lung cancer, esophageal cancer, breast cancer, stomach cancer, colorectal cancer, liver cancer, and pancreatic cancer.
- Non-cancer group: Individuals who have not been diagnosed with cancer during routine physical examinations and one-year follow-up.
Exclusion
- Uncontrolled or active systemic diseases, such as autoimmune diseases, tuberculosis, AIDS, etc.
- New onset, recurrence, or exacerbation of various inflammations within 2 weeks before blood collection, or the presence of fever, use of corticosteroids.
- New onset or exacerbation of thromboembolic diseases, hemorrhagic diseases, or those who have received allogeneic blood transfusion within 1 month before blood collection.
- Any cancer treatment performed within the past 3 years.
- Individuals who have undergone organ or bone marrow transplantation.
- Participants during pregnancy or lactation.
- Individuals with malnutrition, severe mental illness, or genetic diseases.
- Other diseases or conditions deemed by the physician as unsuitable for participation in this study.
- Individuals who are unable to sign an informed consent form.
Key Trial Info
Start Date :
September 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
3200 Patients enrolled
Trial Details
Trial ID
NCT06036563
Start Date
September 1 2023
End Date
December 1 2025
Last Update
May 16 2024
Active Locations (8)
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1
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guangzhou, Guangdong, China, 510000
2
The First Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China, 510000
3
First Hospital of China Medical University
Shenyang, Liaoning, China, 110000
4
People's Hospital of Ningxia Hui Autonomous Region
Yinchuan, Ningxia, China, 750000