Status:

UNKNOWN

Resistant Bacteria in Children in France

Lead Sponsor:

Association Clinique Thérapeutique Infantile du val de Marne

Collaborating Sponsors:

Pfizer

Conditions:

Infection Due to Resistant Bacteria

Multi-antibiotic Resistance

Eligibility:

All Genders

Up to 17 years

Brief Summary

This study is observational, multicenter and prospective study for surveillance of the use of new antibiotics in pediatrics for treated pediatrics infections due to multi-resistant bacteria

Detailed Description

The main of this study is to evaluate the relevance of prescribing "new antibiotics" according to the antibiogram of the isolated bacteria or in the absence of bacteriological documentation As this i...

Eligibility Criteria

Inclusion

  • Children under 18 years of age
  • Hospitalized in France in a hospital center working with the ACTIV/GPIP network
  • Treated with one or more of the following antibiotics:
  • Colimycin (Colistimethate sodium)
  • Cefiderocol
  • Aztreonam in combination
  • Ceftolozane-Tazobactam
  • Ceftazidime-avibactam
  • Meropenem/vaborbactam
  • Imipenem/Relebactam
  • Tigecycline
  • Daptomycin
  • Ceftaroline fosamil
  • Tedizolid phosphate
  • Fidaxomicin
  • Ceftobiprole
  • Dalbavancin
  • In association with a documented infection performed by:
  • Blood culture
  • Normally sterile site
  • Cerebrospinal fluid
  • Pleural fluid
  • Pleura
  • Peritoneum
  • Joint fluid
  • Other
  • Urine sampling if the bacteria was considered responsible for the infection (associated with a leukocyturia ≥10,0000)
  • Respiratory specimens if the bacteria was considered responsible for the infection
  • Sampling on material such as:Intubation probe, Orthopedic, Urological, Central Nervous System (CNS),....
  • Related to colonization with multidrug-resistant bacteria without documentation.

Exclusion

  • Refusal of participation by the patient or his/her parent
  • Medical history of mucoviscidosis

Key Trial Info

Start Date :

April 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 31 2025

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT06036628

Start Date

April 1 2023

End Date

March 31 2025

Last Update

February 8 2024

Active Locations (1)

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1

ACTIV

Créteil, France, 94000