Status:

COMPLETED

Assessement of the Soothing Effect of a Food Supplement on Sensitive and Reactive Skin

Lead Sponsor:

Seppic

Conditions:

Healthy Volunteers

Eligibility:

FEMALE

18-65 years

Phase:

NA

Brief Summary

The study is aimed to assess the soothing effect of a food supplement composed of Coriander Seed Oil (CSO) in terms of reducing skin redness and skin discomfort (stinging feeling) on sensitive and rea...

Detailed Description

A double blind, parallel groups, placebo-controlled study is carried out on 80 female subjects aged between 18 and 65 years old with sensitive and reactive skin. The study foresees 56 days of product...

Eligibility Criteria

Inclusion

  • Inclusion criteria :
  • Good general health
  • Caucasian ethnicity
  • Female sex
  • Phototype I to IV
  • Sensitive and reactive skin (showing positive answer from 3-moderate to 4-strong to stinging test performed with a 10% lactic acid solution)
  • Age between 18 and 65 years old (subject with 18 and 65 years old can be included)
  • Subjects who have not been recently involved in any other similar study (evaluation is performed case by case by the experimenter but at least 1 month must be elapsed between a previous study on food supplement)
  • Willingness to use during all the study period only the products to be tested
  • Willingness not to use similar products that could interfere with the product to be tested
  • Willingness to not vary the normal daily routine (i.e. lifestyle, physical activity, diet etc.)
  • Subjects under effective contraception (oral/not oral) if women of childbearing potential; not expected to be changed during the trial
  • Subject aware of the study procedures and having signed an informed consent form
  • Subjects who accept not to expose in intensive way to UV rays during the whole study duration
  • Subjects who have not involved in any sun test (for SPF evaluation) or tests that provide skin irradiation since less than two months
  • Exclusion Criteria:
  • Subject does not meet the inclusion criteria,
  • Pregnant/breastfeeding female or who have planned a pregnancy during the study period
  • Subjects under systemically pharmacological treatment
  • Subjects under locally pharmacological treatment on the skin area monitored during the test
  • Subjects with congenital or acquired immunodeficiency
  • Subjects under treatment with food supplements which could interfere with the functionality of the product under study
  • Subjects which show skin alterations on the monitored area which could interfere with the functionality of the product under study
  • Subjects considered as not adequate to participate to the study by the investigator
  • Subjects with known or suspected sensitization to one or more test formulation ingredients
  • Adult protected by law (under control or hospitalized in public or private institutions for reasons other than research, or incarcerated)
  • Subjects not able to communicate or cooperate with the investigator for problems related to language, mental retardation or impaired brain function

Exclusion

    Key Trial Info

    Start Date :

    October 15 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    January 31 2022

    Estimated Enrollment :

    80 Patients enrolled

    Trial Details

    Trial ID

    NCT06037291

    Start Date

    October 15 2021

    End Date

    January 31 2022

    Last Update

    September 14 2023

    Active Locations (1)

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    Complife Italia srl

    Milan, Italy, 20024