Status:

UNKNOWN

Plasma Sodium and Sodium Administration in the ICU

Lead Sponsor:

University Hospital, Linkoeping

Conditions:

Hypernatremia

Hyponatremia

Eligibility:

All Genders

18+ years

Brief Summary

Patients in the Intensive Care Unit often present with low levels of plasma sodium and are therefore often administered high amounts of sodium, both as an additive to intravenous glucose solutions and...

Detailed Description

Treatment with intravenous fluids (fluid therapy) is a cornerstone in intensive care. The primary aim of fluid therapy is to optimize the amount of fluid in the various spaces of the body: intravascul...

Eligibility Criteria

Inclusion

  • Adult
  • Documented length of stay at the Central Intensive Care Unit (CIVA) at the University Hospital of Linköping of seven (7) days minimum.
  • The patient has been discharged from the ICU.
  • Body Mass Index (BMI) between 18.0 and 48.0 kg/m2 at admission.

Exclusion

  • The patient has previously been included in the study in connection with another ICU-admission.
  • The patient has a severe hyponatremia (\<129 mmol/L) upon arrival to the ICU.
  • The patient has a severe hypernatremia (\>149 mmol/L) upon arrival to the ICU.
  • The patient is severely hyperosmolar (\>330 mmol/L) upon arrival to the ICU.
  • The patient is severely hyperglycemic (\>30 mmol/L) upon arrival to the ICU.
  • The patient has an elevated serum urea (\>30 mmol/L) upon arrival to the ICU.
  • The patient receives any dialysis treatment during the observation time.
  • The patient is suspected to have an elevated intracranial pressure during the observation time or is suspected to have other intracranial pathology that is likely to affect sodium homeostasis
  • The patient has an intoxication with toxic alcohols as a primary diagnosis.

Key Trial Info

Start Date :

September 4 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2024

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06037928

Start Date

September 4 2023

End Date

January 31 2024

Last Update

September 26 2023

Active Locations (1)

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1

University Hospital Linköping

Linköping, Sweden, 58185