Status:
RECRUITING
Optimizing Pain Self-Management in Total Knee Arthroplasty
Lead Sponsor:
University of Virginia
Conditions:
Osteo Arthritis Knee
Knee Pain Chronic
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate the efficacy of a positive affect enhancing intervention designed to reduce pain and augment reward system function in knee osteoarthritis (KOA) patients un...
Detailed Description
Total knee arthroplasty (TKA) is an increasingly utilized, end-stage, cost-effective treatment for knee osteoarthritis (OA), one of the leading causes of disability worldwide whose hallmark symptoms i...
Eligibility Criteria
Inclusion
- 18-85 years old.
- Have a physician-confirmed treatment plan to undergo unilateral TKA along with physician-confirmed knee osteoarthritis diagnosis.
- Willingness and ability to comply with scheduled sessions and study procedures
Exclusion
- Member of a vulnerable population including pregnant women, children, prisoners, cognitively impaired, and non-English-speaking subjects.
- Current unstable, severe medical comorbidity.
- Current severe psychiatric comorbidity (e.g., schizophrenia, psychosis, or other unstable psychiatric disorder).
- Current severe alcohol or substance use disorder.
- Weekly or more frequent use of opioids in the past 30 days (other than tramadol and/or codeine) for therapeutic or non-therapeutic purposes.
- Other surgery of the affected knee in the last 6 months.
- Previous TKA.
Key Trial Info
Start Date :
November 27 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06038240
Start Date
November 27 2023
End Date
September 1 2027
Last Update
December 6 2023
Active Locations (1)
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1
Fontaine Research Park
Charlottesville, Virginia, United States, 22903