Status:

NOT_YET_RECRUITING

Indocyanine Green for Detection of Sentinel Lymph Nodes In Comparison to ICG Plus Technetium in the Evaluation of Vulvar Squamous Cell Carcinoma

Lead Sponsor:

Hamilton Health Sciences Corporation

Collaborating Sponsors:

Juravinski Cancer Centre Foundation

Conditions:

Vulvar Cancer

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

Brief Summary

The aim of this study is to confirm prospectively if the use of near infrared-indocyanine green (NIR-ICG) alone offers similar accuracy and sensitivity to the gold standard dual technique for sentinel...

Eligibility Criteria

Inclusion

  • Adult women (18 years of age) with FIGO Stage IB (\> 1 mm depth of invasion) and small Stage II (4 cm) vulvar squamous cell carcinoma or cutaneous melanoma who are candidates for the Sentinel lymph node technique will be included (Negative clinical groin examination and/or imaging and primary unifocal vulvar tumor size of \< 4 cm).

Exclusion

  • Women with a prior history of pelvic, vulvovaginal or inguinal radiation, with allergy or hypersensitivity to Technetium or ICG, or Bartholin gland cancer will be excluded.

Key Trial Info

Start Date :

October 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

58 Patients enrolled

Trial Details

Trial ID

NCT06039111

Start Date

October 1 2023

End Date

June 30 2026

Last Update

September 15 2023

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