Status:

UNKNOWN

Using of Collagen Matrix for Maxillary Tuberosity Donor Area Preservation

Lead Sponsor:

I.M. Sechenov First Moscow State Medical University

Conditions:

Soft Tissue Atrophy

Eligibility:

All Genders

18-45 years

Phase:

NA

Brief Summary

An interventional prospective randomised clinical trial (RCT) in parallel groups is planned. The sample size was 30 patients who will be randomly divided into two groups based on the surgical procedur...

Detailed Description

The aim of this study is to perform a comparative analysis of the effectiveness of using a double-layer collagen matrix to preserve the parameters of the donor area in the region of the maxillary tube...

Eligibility Criteria

Inclusion

  • Presence of written informed consent of the patient to participate in the study;
  • Age between 18 and 45 years;
  • Included defects on the maxilla or mandible within 1-2 teeth combined with soft tissue thickness deficiency in the area of dental implants (\< 2 mm);
  • Teeth without periodontal pathology, probing depth should not exceed 3 mm across the entire dentoalveolar sulcus;
  • Satisfactory level of oral hygiene;
  • Absence of general diseases in the stage of exacerbation or decompensation
  • Non-inclusion criteria:
  • Patients who had previous harvesting of CTG from the same donor area;
  • Patients with impacted third molars in the donor area;
  • Presence of concomitant diseases in the stage of exacerbation or decompensation;
  • Patients with oncological diseases, as well as patients who have received radiotherapy and chemotherapy in the last 5 years;
  • Patients with a history of smoking for more than 10 years.

Exclusion

  • Patient refusal of further participation in the study;
  • Pregnant and breastfeeding women;
  • Patients with blood coagulation disorders (haemophilia, Willebrand's disease, intake of anticoagulants);
  • Patients with diseases that impair soft tissue healing (insulin-dependent diabetes mellitus).

Key Trial Info

Start Date :

January 17 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 15 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06039839

Start Date

January 17 2023

End Date

May 15 2025

Last Update

September 15 2023

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I.M. Sechenov First Moscow State Medical University (Sechenov University)

Moscow, Russia