Status:
COMPLETED
Retrospective Study in FFPE Samples From Younger Patients With Rhabdomyosarcoma
Lead Sponsor:
Shandong First Medical University
Collaborating Sponsors:
Shandong Tumor Hospital
Conditions:
Alveolar Childhood Rhabdomyosarcoma
Embryonal Childhood Rhabdomyosarcoma
Eligibility:
All Genders
1-18 years
Brief Summary
This retrospective study is looking into mechanisms of drug therapy resistance in FFPE samples in recurrent and refractory Rhabdomyosarcoma (RMS) in pediatric patients who have experienced lung recurr...
Detailed Description
This research seeks to enhance our understanding of drug resistance mechanisms in recurrent and refractory RMS in pediatric patients, particularly in the context of lung recurrence. The utilization of...
Eligibility Criteria
Inclusion
- Pediatric Patients: Participants in this study should be pediatric patients, typically defined as individuals aged from infancy to 18 years old, who have been diagnosed with recurrent and refractory Rhabdomyosarcoma (RMS).
- Lung Recurrence: Included patients must have a documented history of lung recurrence of RMS as a specific clinical manifestation.
- Availability of FFPE Samples: Patients for whom formalin-fixed paraffin-embedded (FFPE) tissue samples are available for analysis are eligible for inclusion.
Exclusion
- Other Histological Types: Patients with RMS of histological subtypes other than those relevant to the study focus are excluded.
- Incomplete Clinical Data: Patients with incomplete or insufficient clinical data necessary for the study's objectives may be excluded to ensure robust analysis and interpretation of results.
Key Trial Info
Start Date :
April 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2023
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT06040229
Start Date
April 1 2023
End Date
September 1 2023
Last Update
September 15 2023
Active Locations (1)
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1
Jinan central hospital affiliated to Shandong First Medical University
Jinan, Shandong, China, 250017