Status:
COMPLETED
Guiding Opioid Administration in Patients With Regional Anesthesia
Lead Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Conditions:
Nociceptive Pain
Pain, Postoperative
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
General anesthesia is a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception. An alternative approach to the intraoperative administration of high p...
Detailed Description
General anesthesia is a combination of hypnotic drugs and opioid analgesics. Modern general anesthesia aims to treat nociception induced by surgical stimulation while avoiding an overdose of opioid an...
Eligibility Criteria
Inclusion
- Patients having elective trauma or orthopaedic surgery with a combination of general and regional anaesthesia
Exclusion
- Preexisting therapy with beta-blockers, cardiac glycosides or pacemakers
- Cardiac arrhythmia (atrial fibrillation, atrioventricular block \> I°)
- Intraoperative treatment with ketamine, beta blockers, beta-adrenergic agonists or clonidine
- Serious peripheral or cardiac autonomic neuropathy
- Inability to specify the postoperative pain level
- Postoperative treatment in an Intensive Care Unit
Key Trial Info
Start Date :
December 18 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 6 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06040307
Start Date
December 18 2023
End Date
May 6 2024
Last Update
May 13 2024
Active Locations (1)
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1
Department of Anesthesiology; Center of Anesthesiology and Intensive Care Medicine, Hamburg Eppendorf University Medical Center
Hamburg, Germany, 20246