Status:
UNKNOWN
Antiperistaltic Effect and Safety of Glycopyrronium for Colonoscopic Polypectomy
Lead Sponsor:
Jie Chen
Conditions:
Glycopyrrolate
Colonoscopy
Eligibility:
All Genders
18-80 years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to determine the antiperistaltic effect and safety of glycopyrrolate and whether the use of glycopyrrolate is beneficial for colonoscopy and colonoscopic polypectomy.
Detailed Description
Colonic spasm is a major adverse event affecting colonoscopy.The current mainstay for the prevention of colonic spasm is the use of antispasmodic.Glycopyrrolate is a long-acting quaternary ammonium an...
Eligibility Criteria
Inclusion
- Age 18-80 years old.
- Outpatients and inpatients with lesions to be resected under colonoscopy.
- Participants voluntarily participated and signed informed consent forms.
Exclusion
- Pregnancy status and lactating women.
- With glaucoma, myasthenia gravis, hyperthyroidism, chronic renal insufficiency, and inflammatory bowel disease.
- With obstructive gastrointestinal diseases such as pyloric obstruction, paralytic ileus, and achalasia of the cardia.
- With obstructive urinary tract diseases such as prostatic hyperplasia and dysuria.
- With heart disease such as arrhythmia (bradycardia, tachycardia, ventricular fibrillation, atrial fibrillation, etc.), coronary heart disease, congestive heart failure.
- With a history of previous abdominal or intestinal surgery.
- Anticholinergic drugs were administered 48 hours before surgery.
Key Trial Info
Start Date :
October 8 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06041984
Start Date
October 8 2023
End Date
June 1 2024
Last Update
December 8 2023
Active Locations (1)
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1
The Second Affiliated Hospital Of Chongqing Medical University
Chongqing, Chongqing Municipality, China, 400000