Status:

NOT_YET_RECRUITING

Belief-updating, Speech and Psychosis

Lead Sponsor:

King's College London

Conditions:

Psychosis

Eligibility:

All Genders

18-40 years

Brief Summary

Psychotic illnesses are characterised by hallucinations, delusions, and disturbed thoughts; symptoms associated with high personal and societal costs. Despite the efficacy of antipsychotic medication,...

Eligibility Criteria

Inclusion

  • Inclusion criteria (FEP)
  • Participants will be recruited from two routes:
  • Participants who are part of Urban Mind study will be invited to the present study;
  • Patients who are referred to the following early psychosis teams will also be invited to the study: Lambeth Early Psychosis (LEO), Southwark Team for Early Psychosis (STEP), Lewisham Early Intervention Service (LEIS), Croydon Outreach Assessment Support Team (COAST), Central and North West London NHS Foundation Trust (NWLFT).
  • Participants from both routes will need to meet the following criteria:
  • all participants are 18 to 40 years old
  • all participants have an adequate command of the English language to complete the assessment
  • all participants need access to laptop, smartphone or computer to complete the tasks
  • all participants met FEP as defined by a DSM-IV diagnosis of schizophrenia, schizophreniform disorder, schizoaffective disorder, or delusional disorder based on the Structured Clinical Interview for DSM-IV (SCID-I) (First et al., 2002).

Exclusion

  • Exclusion criteria (FEP)
  • Experienced more than one previous episode of psychosis
  • Any other neurological disorders that could potentially interfere with study process or patients' safety
  • Refusing to complete the belief-updating or speech tasks
  • Participants' answers are identified as fake answers or participants complete the tasks for multiple times (identified by their unique participants code).
  • Participants are unable to fully comprehend the purpose of the study or make a rational decision whether or not to participate

Key Trial Info

Start Date :

May 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 30 2028

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT06042712

Start Date

May 1 2024

End Date

April 30 2028

Last Update

March 6 2024

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