Status:

COMPLETED

Analgesic Efficacy of Free-opioid Anesthesia for Colorectal Surgery

Lead Sponsor:

Vietnam Military Medical University

Conditions:

Colorectal Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Objectives: To compare free-opioid anesthesia (the combination of epidural anesthesia, intravenous lidocaine, ketamine, propofol, and sevoflurane) and opioid anesthesia (fentanyl, propofol and sevoflu...

Detailed Description

After being placed an epidural catheter and given a bolus dose of dexamethasone 0.1 mg/kg, patients was endotracheal anesthetized with propofol 1% 2-2.5 mg/kg, rocuronium 0.6 mg/kg. Intubation was imp...

Eligibility Criteria

Inclusion

  • Patients agreed to participate in the study.
  • Patients aged ≥ 18 years old,
  • Those who underwent elective colectomies or rectal resections,
  • Those who were ASA (American Society of Anesthesiologists) classified as I - III,
  • Those who were indicated for general endotracheal anesthesia from December 2019 to November 2021 at Viet Tiep Friendship Hospital

Exclusion

  • Patients refused to participate in the study,
  • Patients had BMI (Body Mass Index) ≥ 35;
  • Pregnant or lactating or menstruating women;
  • Those who had liver failure, renal failure, heart failure, history of chronic pain, alcohol or drug abuse, mental illnesses, allergies or contraindications to any studied medications.
  • Those who were unable to assess pain or use of patient-controlled analgesia devices (PCA).

Key Trial Info

Start Date :

December 30 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2021

Estimated Enrollment :

49 Patients enrolled

Trial Details

Trial ID

NCT06042816

Start Date

December 30 2019

End Date

December 30 2021

Last Update

September 21 2023

Active Locations (1)

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Viet-Tiep Friendship Hospital

Haiphong, Le Chan, Vietnam, 184570