Status:

RECRUITING

MMR/MSI Phenotypes in Prediction of Tumor Vaccine Benefit for Gliomas

Lead Sponsor:

Huashan Hospital

Conditions:

Glioma

Eligibility:

All Genders

18-80 years

Brief Summary

Glioblastoma (GBM) is the most malignant primary intracranial tumor with a median survival of about 18 months, and new therapies are urgently needed. Tumor vaccines has been shown to improve survival ...

Eligibility Criteria

Inclusion

  • The patients with glioma in the Department of Neurosurgery of Huashan Hospital Affiliated to Fudan University who meet the following three conditions can be enrolled
  • They were 18-80 years old, male and female;
  • The pathological results of frozen section during operation were gliomas (20 cases of who grade II, II and IV, respectively);
  • Tissue (6 mm \* 6 mm) can be used for cell sorting on the basis of not affecting clinical routine diagnosis;
  • Sign informed consent.

Exclusion

  • Patients who meet any of the following criteria will not be included in this study:
  • Participants in other clinical trials;
  • Pregnant women.

Key Trial Info

Start Date :

September 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2026

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT06043232

Start Date

September 1 2023

End Date

March 1 2026

Last Update

September 21 2023

Active Locations (1)

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1

Huashan Hospital,Fudan University

Shanghai, China, 200040