Status:
RECRUITING
Impact of an Echographic Algorithm on Hemodynamic Optimization in the First 4 Days of Septic Shock Management
Lead Sponsor:
Centre Hospitalier Universitaire de Nīmes
Conditions:
Shock, Septic
Hemodynamic Instability
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Fluid management is one of the key issues in the initial management of septic shock (SS). Fluid overload and hypovolemia have been associated with increased mortality in several trials. Transthoracic ...
Eligibility Criteria
Inclusion
- All eligible patients will have a cardiac echocardiogram prior to inclusion for the sole purpose of eliminating special situations that are part of the non-inclusion criteria listed below.
- Inclusion Criteria
- Patient in an intensive care unit who develops septic shock on admission or during hospitalization, as defined by SEPSIS-3 criteria.
- Patient or trusted person / legal representative / family member / curator / guardian who has given free and informed consent and has signed the consent form or patient included in an emergency situation.
- Patient affiliated or beneficiary of a health insurance plan.
- Patient at least (≥) 18 years of age.
- Exclusion Criteria:
- Refusal of consent.
- Patient under court protection or guardianship.
- Moribund patient with a life expectancy of less than 48 hours.
- Non-echogenic patient.
- Cardiac tamponade.
- Infective endocarditis.
- Intracavitary thrombus.
- Dilated cardiomyopathy with LVEF (Left Ventricular Ejection Fraction\<40%.
- Parturient or nursing patient.
Exclusion
Key Trial Info
Start Date :
February 8 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 26 2024
Estimated Enrollment :
136 Patients enrolled
Trial Details
Trial ID
NCT06043505
Start Date
February 8 2024
End Date
October 26 2024
Last Update
March 15 2024
Active Locations (1)
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1
CHU de Nimes
Nîmes, France, 30029