Status:
RECRUITING
Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic Dissection
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Aortic Dissection
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Acute DeBakey type I aortic dissection (ATAD) is one of the most lethal surgical emergencies. The conventional operative strategy is hemiarch replacement under cardiopulmonary bypass support to replac...
Detailed Description
Project Objectives 1. To compare the occurrence of Distal Anastomosis New Entry (DANE) after conventional hemiarch replacement group (Hemiarch-C) and the hemiarch replacement plus AMDS implantation g...
Eligibility Criteria
Inclusion
- Patient´s age is between 18 and 80 years.
- Patient is willing and able to give informed consent.
- Patient has acute DeBakey Type I and requires repair or replacement of damaged or diseased vessels of the ascending aorta.
- Patient not in coma/irreversible end organ failure/cardiac massage for resuscitation, at the time of consent.
Exclusion
- Patient has aortic arch diameter of more than 4.5 cm
- Patient has known connective tissue disease or genetically linked aortopathy
- Patient has entry tear more than 2 cm over aortic arch
- Patient with DeBakey Type II aortic dissection
- Patient has co-morbidity (i.e. active malignancy (progressive, stable or partial remission)) causing expected survival to be less than 2 years.
- Patient has any other medical, social, or psychological problems, that in the opinion of the investigator, preclude the patient from participating in this study.
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2027
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT06044259
Start Date
October 1 2023
End Date
September 30 2027
Last Update
September 29 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Prince of Wales Hospital
Hong Kong, Hong Kong, China, 000