Status:
RECRUITING
Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain
Lead Sponsor:
Rush University Medical Center
Collaborating Sponsors:
Wayne State University
Conditions:
Chronic Pain
Neck Pain
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Chronic musculoskeletal pain (CP) is a major public health concern. Psychosocial treatments have been shown to be efficacious when compared to largely inert control conditions, but they are characteri...
Detailed Description
Chronic musculoskeletal pain (CP) is a major public health concern. A number of psychosocial treatments have emerged in recent decades to help address this problem. These interventions have been shown...
Eligibility Criteria
Inclusion
- Back/neck is primary pain location (e.g., back/neck pain greater than leg pain)
- Pain for at least 3 months and experienced 4 or more days/week for the past 6 months
- Pain intensity last week is \>= 3 (0 to 10 rating scale)
- Pain interference last week is \>= 3 (0 to 10 rating scale)
- At least age 18
- Lives in United States
- Fluent in English
- Has personal computer/tablet and internet access
- Able to attend weekly sessions
- Willing to be randomized
- Seeking to improve their pain-related status via a psychological therapy
Exclusion
- Past 2 years (treated for or having experienced):
- Complex regional pain syndrome
- Epilepsy/seizure disorder
- Autoimmune disease
- Liver disease
- Cancer
- Heart disease
- Substance dependence or use disorder
- Schizophrenia or other psychotic disorder
- Bipolar disorder
- Obsessive-compulsive disorder
- Borderline personality disorder
- Suicide attempt or suicide intention or impulse
- Also:
- Major medical procedure scheduled within next 9 months
- Applied for/ litigating for pain-related disability/worker's compensation (past year).
- Major life event/stressor in past 6 months
- Cognitive impairment (screener score \<=4)
Key Trial Info
Start Date :
November 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 30 2027
Estimated Enrollment :
460 Patients enrolled
Trial Details
Trial ID
NCT06044649
Start Date
November 15 2023
End Date
March 30 2027
Last Update
April 25 2025
Active Locations (2)
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1
Rush University Medical Center
Chicago, Illinois, United States, 60612
2
Wayne State University
Detroit, Michigan, United States, 48202