Status:
COMPLETED
Nd-YAG Laser Versus Epidermal Growth Factor For Myogenic Tempromandibular Disorder.
Lead Sponsor:
Alexandria University
Conditions:
Temporomandibular Joint Disorders
Eligibility:
All Genders
20+ years
Phase:
PHASE4
Brief Summary
A clinical trial comparing the potential effect of 2 different modalities (Nd-YAG Laser Versus Epidermal growth factor injection) on pain reduction in patients suffering from myogenic tempromandibular...
Detailed Description
Background: Tempromandibular disorders (TMDs) form a public health issue and are considered the second most common musculoskeletal problem (after chronic lower back pain) causing pain and disability. ...
Eligibility Criteria
Inclusion
- Patients, both males and females, 20 years and older will be included in this clinical trial.
- Patients suffering from myogenic TMD (myogenic TMD/ Myofascial pain without referral/ Myofascial pain with referral) based on Diagnostic criteria for diagnosis of Tempromandibular joint disorders (DC/TMD) criteria (1)
- Patients suffering of unilateral or bilateral chronic pain (\> 3 months duration) related to masseter and temporalis muscles (29)
- Patients that have not responded to conservative modes of treatment (analgesics, muscle relaxants, fomentation, splints ect.).
Exclusion
- Patients suffering from any condition that could alter pain sensitivity; neurological diseases, pain of dental origin, pregnancy or lactation, high blood pressure, diabetes mellitus, rheumatic inflammatory disease, fibromyalgia, obstructive sleep apnea, skin infection over injection areas related to masseter and temporalis muscles, and restrictions for the use of laser (pacemakers) (6, 20, 30) 2. Participants on medications that can affect pain sensitivity and pain perception; anticoagulants, analgesics, antidepressants during the last 2 weeks before the study (6, 20) 3. Smokers or those with conditions that could affect saliva collection or composition; hyposalivation, poor oral hygiene, periodontitis and oral mucosal diseases
Key Trial Info
Start Date :
January 21 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 10 2024
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT06044974
Start Date
January 21 2023
End Date
January 10 2024
Last Update
August 1 2024
Active Locations (1)
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1
Alexandria University
Alexandria, Alexandria Governorate, Egypt