Status:
COMPLETED
Aromatherapy in Total Knee Replacement
Lead Sponsor:
Hospital for Special Surgery, New York
Conditions:
Total Knee Replacement
Post-operative Nausea and Vomiting
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this pilot randomized controlled trial is to investigate the effects of aromatherapy on postoperative anxiety and pain in total knee replacement patients. The primary research questions...
Detailed Description
Preoperative depression, anxiety, and catastrophizing have all been linked to an increase in postoperative pain and opiate use. Although aromatherapy, specifically lavender, may lower anxiety, no plac...
Eligibility Criteria
Inclusion
- Age \> 18 and ≤ 80
- Scheduled to undergo primary, unilateral knee replacement surgery
- Willing and able to provide informed consent
- Willing and able to complete follow-up procedures
- Intact olfactory function
- Score 19 or greater on the PROMIS Anxiety Shortform 8A
Exclusion
- Score \<19 on the PROMIS Emotional Distress - Anxiety - Short Form 8a
- Current major anxiety or depression
- Currently taking medications to treat anxiety
- Impaired sense of smell
- History of chronic pain with opioid use for greater than 3 months
- History of Drug or Alcohol abuse
- History of fibromyalgia
- History of G6PD deficiency
- Plant or tree nut allergy
- Severe allergy to Opioids, NSAIDS or local anesthetics (such as anaphylaxis)
- Severe liver disease, renal insufficiency (with inability to take acetaminophen or NSAIDS)
- Non-English Speaking
- Surgery requiring a hospitalization of greater than 3 days
- Patient refusal
- Current cardiac fibrillation
- Chronic opioid user (\>3 months)
- BMI ≥ 45
- Contraindication to neuraxial anesthesia
Key Trial Info
Start Date :
October 3 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2024
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06045078
Start Date
October 3 2023
End Date
April 1 2024
Last Update
January 27 2025
Active Locations (1)
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1
Hospital for Special Surgery
New York, New York, United States, 10021