Status:
COMPLETED
Prediction of Early Recovery of Liver Function After LDLT in Children: An Ambispective Cohort Study
Lead Sponsor:
Huiwu Xing
Conditions:
Liver and Biliary Tract Disorders in Duration of Pregnancy
Other End-stage Liver Diseases in Children
Eligibility:
All Genders
Up to 18 years
Brief Summary
The investigators included children with living donor liver transplantation (LDLT) from January 1, 2018 to July 31, 2022 as a retrospective cohort, and the group from August 1, 2022 to June 30, 2023 a...
Eligibility Criteria
Inclusion
- children with the indication of LDLT \[cholestatic liver disease (such as BA), metabolic liver disease (such as Wilson's disease and Ornithine transcarbamylase deficiency), acute liver failure (such as drug induced), neoplastic disease (such as hepatoblastoma), vascular disease (such as cavernous transformation of portal vein and congenital absence of portal vein), re-transplantation and others\];
- the relatives of the children voluntarily donated part of the liver which met the requirements of LDLT.
Exclusion
- recipients with contraindications of LDLT (such as coagulation dysfunction, acute infection, cardiopulmonary failure);
- failure to complete LDLT due to various reasons (such as death during or within 3 days after operation);
- recipients or donors with incomplete necessary data.
Key Trial Info
Start Date :
July 31 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2023
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT06045949
Start Date
July 31 2022
End Date
September 1 2023
Last Update
September 21 2023
Active Locations (1)
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1
Children's Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China, 400010