Status:
COMPLETED
Left Ventricular Ejection Fraction in Cardiac Arrest Survivors Treated With Extracorporeal Cardiopulmonary Resuscitation
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
URC-CIC Paris Descartes Necker Cochin
Conditions:
Out-of-Hospital Cardiac Arrest
Extracorporeal Cardiopulmonary Resuscitation
Eligibility:
All Genders
18+ years
Brief Summary
Extra-hospital cardiac arrest is a major public health problem, with approximately 46,000 cases per year. Nearly 71% of the patients for whom resuscitation was initiated did not present a return of sp...
Detailed Description
Extra-hospital cardiac arrest is a major public health problem, with approximately 46,000 cases per year. Nearly 71% of the patients for whom resuscitation was initiated did not present a return of sp...
Eligibility Criteria
Inclusion
- Implementation of an extracorporeal membrane oxygenation (ECMO) following an acute coronary syndrome (ACS) defined for the purposes of the study by the existence of at least one of the following criteria: ST segment elevation or depression on the electrocardiogram associated with chest pain and elevated plasma troponin levels; a coronary angiography showing at least one significant coronary lesion and/or having required revascularization. Confirmation of an ischemic etiology by post-mortem examination. A coronary lesion is considered significant if it is described by the cardiologist as: acute and responsible for a reduction in the caliber of the artery strictly greater than 70% and less than 99% for a severe stenosis, and 100% for a complete stenosis.
- Patients hospitalized at Necker Hospital for pre-hospital cardiac arrest between January 1, 2015 and October 31, 2019.
- Sending to living patients of the study information note, a period of one month is given to the patients to oppose the use of their data for the study.
Exclusion
- Extracorporeal membrane oxygenation implementation outside the context of refractory out-of-hospital cardiac arrest
- In-hospital cardiac arrests
- Obvious non-cardiological cause of cardiac arrest
- Cardiac arrests unrelated to acute coronary syndrome
- Cardiac arrests for which no etiology has been found
- Patients opposed to the use of their data
Key Trial Info
Start Date :
April 24 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 4 2024
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT06046339
Start Date
April 24 2024
End Date
May 4 2024
Last Update
September 12 2025
Active Locations (1)
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1
Hôpital Necker-Enfants Malades
Paris, France, 75015