Status:
COMPLETED
Dietary Acid Reduction and Progression of Chronic Kidney Disease
Lead Sponsor:
University of Texas at Austin
Conditions:
Chronic Kidney Diseases
Cardiovascular Diseases
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Upon completion, this project will determine if dietary acid reduction done with either fruits and vegetables (F+V) or the medication sodium bicarbonate (NaHCO3) in study participants with high blood ...
Detailed Description
The long-term objective of this study is to determine if the simple and comparatively inexpensive intervention of dietary acid reduction can prevent or reduce adverse outcomes in individuals with hype...
Eligibility Criteria
Inclusion
- Non-malignant high blood pressure or hypertension
- 18-70 years old
- Urine albumin-to-creatine ratio \> 200 mg/g creatinine
- Estimated glomerular filtration rate (eGFR) greater than or equal to 90 ml/min/1.73 m2
- Serum total CO2 (TCO2) \> 22 mmol/l
- Greater than or equal to 2 primary care visits in the preceding year
- Able to provide informed consent
Exclusion
- Malignant hypertension or history thereof
- Primary kidney disease or findings consistent thereof such as \> 3 red blood cells per high powered field of urine or urine cellular casts
- History of diabetes or fasting glucose greater than or equal to 110 mg/dl
- History of hematologic disorders, malignancies, chronic infections, current pregnancy, history or clinical evidence of cardiovascular disease
- Peripheral edema or diagnosis associated with edema such as heart/liver failure or nephrotic syndrome
- Unable to provide consent
Key Trial Info
Start Date :
June 24 1996
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2011
Estimated Enrollment :
153 Patients enrolled
Trial Details
Trial ID
NCT06046924
Start Date
June 24 1996
End Date
December 15 2011
Last Update
September 21 2023
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