Status:
RECRUITING
Multi-parametric MRI Evaluation of Renal Graft Performance After Living Donor Donation.
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Renal Insufficiency, Chronic
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The selection of kidneys from living donors is based on strict glomerular filtration rate (GFR) values, in the setting of the increasing proportion of older donors. The 2017 KDIGO recommendations cons...
Eligibility Criteria
Inclusion
- For recipients:
- Patients with end-stage chronic kidney disease awaiting kidney transplant from a living donor.
- Adult patient
- Consent signed
- effective contraceptive method for women
- Patient affiliated to a social security or beneficiaries of a similar scheme
- For donors:
- Individuals eligible for living kidney donation with GFR \> 60 mL/min/1.73 m².
- Adult patient
- Consent signed
- effective contraceptive method for women
- Patient affiliated to a social security or beneficiaries of a similar scheme
Exclusion
- For the two groups :
- MRI contraindications (claustrophobia, pacemaker, cardioverter defibrillators implantable, mechanical heart valve non MRI-compatible)
- Weight\> 130 kg
- Pregnant, parturient or breastfeeding
- Persons deprived of their liberty by a judicial or administrative decision,
- Adults subject to a legal protection measure (safeguard measure, guardianship, curators)
- subject participating in another research including an exclusion period still in progress at inclusion
- For recipients :
- \- Contraindication to renal graft biopsy (ongoing or uninterrupted anticoagulant or antiplatelet treatment, thrombocytopenia \<100 x 10\^9/L, anemia \<7 g/dL).
Key Trial Info
Start Date :
May 7 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06047106
Start Date
May 7 2024
End Date
September 1 2027
Last Update
May 29 2024
Active Locations (1)
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1
Hôpital Edouard Herriot, Hospices Civils de Lyon
Lyon, France, 69003