Status:

COMPLETED

Respiratory and Hemodynamic Targets During General Anesthesia

Lead Sponsor:

Lars Wiuff Andersen

Conditions:

Patients Undergoing General Anesthesia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This trial is an investigator-initiated, multicenter, randomized, factorial, single-blind trial of multiple hemodynamic and respiratory targets during general anesthesia. These targets include blood p...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years
  • American Society of Anesthesiologists (ASA) classification 3 to 5
  • Planned endotracheal intubation with positive pressure ventilation
  • Expected operating time ≥ 90 minutes
  • Certain types of surgery

Exclusion

  • Inability to obtain consent (e.g., patient is unconscious, hyperacute surgery)
  • Known or suspected pregnancy
  • Out-patient/same-day surgery
  • Intubated prior to surgery
  • Clinical judgement by the anesthesiologist that any of the interventions could be potentially harmful to the patient

Key Trial Info

Start Date :

October 9 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 24 2025

Estimated Enrollment :

485 Patients enrolled

Trial Details

Trial ID

NCT06047119

Start Date

October 9 2023

End Date

April 24 2025

Last Update

August 5 2025

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Aalborg University Hospital

Aalborg, Denmark

2

Aarhus University Hospital

Aarhus, Denmark

3

Gødstrup Regional Hospital

Gødstrup, Denmark

4

Horsens Regional Hospital

Horsens, Denmark