Status:

RECRUITING

Maternal And Infant Antipsychotic Study

Lead Sponsor:

Icahn School of Medicine at Mount Sinai

Collaborating Sponsors:

Erasmus Medical Center

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Antipsychotics

Pregnancy

Eligibility:

FEMALE

18+ years

Brief Summary

The goal of this observational study is to learn about maternal psychiatric course and infant development in pregnant individuals with severe mental illness, comparing those treated with antipsychotic...

Detailed Description

Antipsychotic (AP) medications are widely prescribed for a range of mental illnesses including bipolar disorder and nonaffective psychosis. These disorders usually onset in adolescence or early adulth...

Eligibility Criteria

Inclusion

  • Pregnant
  • Severe mental illness, including:
  • Psychotic disorder (affective and nonaffective)
  • Bipolar disorder
  • History of psychiatric hospitalization, regardless of diagnosis
  • Able to complete study interviews and measures in English, Dutch, or Spanish

Exclusion

  • Active substance use disorder in pregnancy
  • Insufficiently high-functioning to provide full informed consent and/or participate in study procedures

Key Trial Info

Start Date :

September 29 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06049953

Start Date

September 29 2023

End Date

December 1 2027

Last Update

September 29 2025

Active Locations (1)

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Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10029