Status:
COMPLETED
A Comparative Study Between Concomitant Versus Load Therapy in Eradication of Helicobacter Pylori Infection
Lead Sponsor:
Helwan University
Conditions:
H. Pylori Infection
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
All patients who presented with epigastric pain and dyspeptic symptoms will undergo endoscopic gastric biopsies. The patients will be subjected to: Full history taking, clinical examination, liver fu...
Detailed Description
The patients will be randomized (closed envelopes) into one of two groups: 1. patients will receive concomitant therapy comprising of pantoprazole (40 mg twice daily), amoxicillin (1 gm twice a day),...
Eligibility Criteria
Inclusion
- All patients who presented with epigastric pain and dyspeptic symptoms
Exclusion
- Patients recently (within 6 months) treated with anti-H. pylori therapy.
- Allergy to any drugs used in our protocol
- Patients on PPI, antibiotics, and steroid or non-steroidal anti-inflammatory drugs within past one month before randomization.
- Concomitant significant comorbidities (advanced cardiac, renal, hepatic disease).
- Presence of GI malignancy.
- Pregnancy or lactating women.
- Unable or refuse to give consent. -
Key Trial Info
Start Date :
July 21 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 19 2023
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06050824
Start Date
July 21 2022
End Date
July 19 2023
Last Update
September 26 2023
Active Locations (1)
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1
Faculty of Medicine, Helwan University
Cairo, Egypt, 11795