Status:
RECRUITING
Ambulatory Oxygen Therapy for Individuals With Mild-to-moderate Interstitial Lung Disease
Lead Sponsor:
University of Alberta
Collaborating Sponsors:
Alberta Boehringer Ingelheim Collaboration
Conditions:
Fibrotic Interstitial Lung Disease
Eligibility:
All Genders
18-85 years
Phase:
PHASE2
Brief Summary
The investigators plan to conduct a study to find out if giving portable oxygen therapy (during physical activity) to patients with interstitial lung disease will improve quality of life, exercise tol...
Detailed Description
Brief Summary: The investigators plan to conduct a study to find out if giving portable oxygen therapy (during physical activity) to patients with interstitial lung disease will improve quality of li...
Eligibility Criteria
Inclusion
- Individuals with fibrotic ILD (all sub-groups of ILD) who have normal oxygen saturation at rest (SpO2 \> 90%) but develop exertional hypoxemia as demonstrated by a SpO2 = 80-89% with activity (measured during 6MWT).
Exclusion
- Use of home oxygen therapy within the previous year for the management of ILD, co-morbid conditions that may require oxygen therapy (such as COPD, cardiovascular disease, or other illnesses), or individuals that require the use of non-invasive ventilation. Additionally, individuals with significant cardiovascular, metabolic, neuromuscular or any other disease that could contribute to dyspnea or abnormal cardiopulmonary responses to exercise will be excluded. Individuals with musculoskeletal injuries that prevent them from completing cycle ergometry exercise trials and ambulation will also be excluded. Individuals with peripheral vascular disease will be excluded from measurement of vascular function (flow mediated dilation).
Key Trial Info
Start Date :
July 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06053164
Start Date
July 1 2025
End Date
September 1 2026
Last Update
December 3 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Clinical Physiology Laboratory
Edmonton, Alberta, Canada, T6G2R3