Status:

RECRUITING

Effects of Clear Speech on Listening Effort and Memory in Sentence Processing

Lead Sponsor:

University of Utah

Conditions:

Speech

Memory, Delayed

Eligibility:

All Genders

60-90 years

Phase:

NA

Brief Summary

Sensorineural hearing loss (SNHL) is among the most prevalent chronic conditions in aging and has a profoundly negative effect on speech comprehension, leading to increased social isolation, reduced q...

Detailed Description

This experiment is a Basic Experimental Study with Humans (BESH) Trial. All participants are exposed to all experimental conditions (i.e., "interventions") in a complete factorial 2 x 3 within-subject...

Eligibility Criteria

Inclusion

  • Age 60-90
  • Right-handed
  • Native English speaker
  • Scores in the normal range (\> or = 25 points) on Montreal Cognitive Assessment (MoCA)
  • For adults with hearing loss, a pure-tone average score of \> 25 dB HL (between 1 - 4kHz)

Exclusion

  • Left-handed (language-related electrophysiological responses of left-handed subjects differ from those of right-handed subjects)
  • History of psychiatric or neurological illnesses (including skull fractures, as this is known to alter electrophysiological response at the scalp)
  • Score of \< 25 points on the MOCA
  • Use of certain prescription and non-prescription drugs known to alter brain function and the autonomic nervous system, including pupil dilation (e.g., anti-depressants, attention deficit hyperactivity disorder drugs)
  • Any eye disease that would impair the ability to measure pupil dilation (e.g., cataracts, nystagmus, amblyopia)
  • Scores on speech shadowing audibility control task below 50%, suggesting poor intelligibility
  • A display of behavior that would significantly interfere with the validity of data collection or safety during the study;

Key Trial Info

Start Date :

September 12 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06053190

Start Date

September 12 2023

End Date

March 1 2025

Last Update

January 13 2025

Active Locations (1)

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1

University of Utah

Salt Lake City, Utah, United States, 84109