Status:
UNKNOWN
The Effect of Exercise and Presleep Nutrition on Muscle Connective Tissue Remodelling
Lead Sponsor:
University of Toronto
Conditions:
Interventional
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
The primary objective of this study will be to determine the influence of a presleep vitamin C-enriched, collagen-modelled supplement (CVC) on the metabolic fate of dietary glycine using a \[2H5\]glyc...
Eligibility Criteria
Inclusion
- Healthy, recreationally active, male and female participants.
- Healthy will be defined as someone who does not have a health condition that would compromise their ability to safely participate in the strenuous physical activity involved in our study as screened for by the Get Active Questionnaire.
- Willing to abstain from resistance exercise for 2 weeks prior to the first metabolic trial and for the duration of the study.
- Participants must be able to abstain from lower-body resistance and/or plyometric exercise for at least 2 weeks prior to the first metabolic trial.
- Participants will be aged 18-35 years old.
- Participants must be normal to overweight (e.g., BMI 18.5-30).
- Participants are willing to abide by the compliance rules of this study (e.g., abstain from physical activity and alcohol 48h prior to each trial).
- Self-reported regular menstrual cycle (25-35d) within the last 3 months (female participants).
Exclusion
- Inability to adhere to any of the compliance rules judged by principal investigator or medical doctor.
- Self-reported regular tobacco use.
- Self-reported illicit drug use (e.g. growth hormone, testosterone, etc.).
- Regular use of anti-inflammatory drugs (e.g., ibuprofen).
- Self-reported regularly sleeping less than an average of 7 hours over 3 days (minimum recommended daily amount).
- Individuals who have participated in studies within the past year involving any of the stable isotopes in the study.
- Use of birth control and discontinued use in the last 3-months (female only).
Key Trial Info
Start Date :
September 15 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2025
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT06054620
Start Date
September 15 2023
End Date
August 1 2025
Last Update
November 13 2023
Active Locations (1)
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1
Goldring Centre for High Performance Sport at the University of Toronto
Toronto, Ontario, Canada, M5S 2C9