Status:

COMPLETED

POTS-CFS Study: Orthostatic Intolerance in the Context of Pediatric ME/CFS

Lead Sponsor:

Technical University of Munich

Collaborating Sponsors:

University Hospital, Aachen

Conditions:

Chronic Fatigue Syndrome in Adolescence

Postural Orthostatic Tachycardia Syndrome

Eligibility:

All Genders

14-17 years

Brief Summary

Pilot-case-control study on exertion and orthostatic intolerance of adolescents with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) compared to age-matched healthy controls (HC).

Detailed Description

ME/CFS is a complex disease. Symptoms include orthostatic intolerance (OI) such as postural tachycardia syndrome (PoTS). PoTS in ME/CFS can significantly impair everyday function and social participat...

Eligibility Criteria

Inclusion

  • Cases (ME/CFS):
  • \- ME/CFS diagnosed by the indicated clinical criteria
  • Healthy Controls
  • clinically healthy
  • no known underlying disease
  • no prescription medication (except contraception)

Exclusion

  • Any contraindication for NASA lean test (cardiac failure, severe aortic stenosis, inability to stand)
  • pregnancy
  • breastfeeding.

Key Trial Info

Start Date :

December 6 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 22 2022

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06054958

Start Date

December 6 2021

End Date

November 22 2022

Last Update

September 26 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

MRI Chronic Fatigue Center for Young People (MCFC) Children's Hospital, Technical University of Munich & Munich Municipal Hospital Munich

Munich, Bavaria, Germany, 80804