Status:

UNKNOWN

Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients

Lead Sponsor:

Danone Specialized Nutrition

Conditions:

Malnutrition

Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This study aims to compare nutritional outcomes in terms of percentage of weight gain between a new planted-based high-energy ONS and a standard high-energy ONS with animal protein (cow's mil protein)...

Detailed Description

Due to the increasingly pressing need to develop an oral nutritional supplement (ONS) that does not contain animal ingredients, Fortimel PlantBased, suitable for patients with Disease-Related Malnutri...

Eligibility Criteria

Inclusion

  • Patients ≥ 18 years old
  • Malnourished patients according to GLIM criteria
  • Patients with a high energy requirement (1.5kcal/ml) requiring the intake of 2 bottles of ONS per day for at least 12 weeks
  • Patients presenting any of the following clinical situations:
  • Elderly patients requiring oral nutritional support
  • Patients with digestive pathology including but not restricted to inflammatory bowel disease, short bowel syndrome, pancreatitis, without active malabsorption and maldigestion.
  • Chronic diseases such as COPD, mild to moderate renal disease, HIV
  • Oncologic patients with Eastern Cooperative Oncology Group (ECOG) 0-1
  • Patients who have given their consent to participate
  • Patients who, in the opinion of the physician, have the capacity to answer the study questionnaires themselves or their caregivers

Exclusion

  • Patients who need ONS due to surgical or acute illness\*
  • Patients with known intolerance or allergy to cow's milk, soya or peas
  • Patients with hyperthyroidism. Patients with uncontrolled hypothyroidism
  • Uncontrolled diabetic patients (HbA1c \>8%)
  • Patients requiring enteral nutrition by tube or ostomy
  • Patients with moderate and serious renal insufficiency \< 30ml/min/1,73 m2
  • Patients who have value creatinine:
  • 1,70 mg/dl - 150,31umol/L Men
  • 1,50 mg/dl - 132,63umol/L Women
  • Patients with levels of haemoglobin \<10 g/dl, transferrin \<150 mg /dl

Key Trial Info

Start Date :

August 9 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 31 2024

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT06055543

Start Date

August 9 2023

End Date

May 31 2024

Last Update

September 26 2023

Active Locations (6)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 2 (6 locations)

1

Hospital Universitario de Basurto

Bilbao, Spain, 48013

2

Hospital Universitario Reina Sofía

Córdoba, Spain, 14004

3

Hospital Universitario de Gran Canaria Doctor Negrín

Las Palmas de Gran Canaria, Spain, 35010

4

Hospital Universitario de Móstoles

Madrid, Spain, 28935