Status:
COMPLETED
Perioperative Blood Adiponectin Dynamics and Systemic Infflamatory Response After Major Colorectal Surgery
Lead Sponsor:
Osijek University Hospital
Conditions:
Obesity, Abdominal
Surgery
Eligibility:
All Genders
18+ years
Brief Summary
Surgical stress after major abdominal surgery in perioperative period causes neuroendocrine, metabolic and imunologic changes in organism with production of proinfflamatory citokines and results with ...
Detailed Description
Gastrointestinal tumors are commonly presented for surgical resections. According to Global Cancer Statistics 2020: GLOBOCAN estimates colorectal carcinoma ranks third in terms of incidence, but secon...
Eligibility Criteria
Inclusion
- Diagnose of colorectal cancer Age \>18 years Patient presenting for major (open) elective colorectal surgery according to carcinoma.
- Written informed consent.
Exclusion
- Age\<18 years BMI\<18.5kg/m2 Acute surgical conditions Established acute systemic/local infection Chronic/actual corticosteroid therapy Active immunomodulation therapy Allergie to used anestehetics/analgetics in study. Patient refusal Laparoscopic surgery Massive intraoperative surgical bleeding Preexisting concomitant second carcinoma other than colorectal origin Patients which does not fulfill inclusion criteria
Key Trial Info
Start Date :
July 27 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 22 2025
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT06057207
Start Date
July 27 2023
End Date
August 22 2025
Last Update
August 29 2025
Active Locations (2)
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1
Osijek University Hospital
Osijek, Osijek, Croatia, 31000
2
Sonja Škiljić
Osijek, Osijek, Croatia, 31000