Status:

RECRUITING

Omega Gastric Bypass (150cm) Compared to the Roux-en-Y Gastric Bypass (YOMEGA-2 Multicentric Trial)

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

Obesity

Morbid

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Obesity with its consequences such as type 2 diabetes, high blood pressure, dyslipidemia, fatty liver disease, sleep apnea and cancers, remains a major healthcare problem worldwide. Bariatric surgery,...

Eligibility Criteria

Inclusion

  • Patient aged from 18 to 65 years old
  • Type III obesity (BMI ≥ 40 kg/m²), or Type II obesity BMI 35-40 kg/m2 associated with at least one co-morbidity which will be improved by surgery (high blood pressure, type 2 diabetes mellitus, obstructive sleep apnea, dyslipidemia, arthrosis)
  • Patient who had benefited from an Upper GI Endoscopy with biopsies to look for Helicobacter pylori within 12 months before surgery
  • Patient who has benefited from a multidisciplinary evaluation at least 6 months, with a favorable opinion for a gastric bypass
  • Patient who understood and accepted the need for a long-term follow-up
  • Patient who agreed to be included in the study and who signed the informed consent form
  • Patient affiliated to a social security scheme
  • For child-bearing aged women, efficient contraception

Exclusion

  • History of previous bariatric surgery
  • History of chronic inflammatory bowel disease
  • Presence of chronic diarrhea
  • Presence of a severe and evolutive life threatening pathology
  • Presence of dysplastic modifications of the gastric mucosa, chronic atrophic gastritis or history of gastric cancer
  • Presence of an unhealed gastro-duodenal ulcer
  • Presence of Helicobacter pylori resistant to medical treatment
  • Presence of esophagitis
  • Pregnancy or desire to be pregnant during the study
  • Mentally unbalanced patients, under supervision or guardianship
  • Patients who don't understand French and not able to give consent
  • Patient included and followed in another interventional trial
  • Unable to consent, under tutelage or curatorship, or judiciary safeguard

Key Trial Info

Start Date :

November 13 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2028

Estimated Enrollment :

368 Patients enrolled

Trial Details

Trial ID

NCT06057597

Start Date

November 13 2023

End Date

December 1 2028

Last Update

November 24 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hôpital Bichat Claude-Bernard

Paris, France