Status:
RECRUITING
Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells
Lead Sponsor:
Jonsson Comprehensive Cancer Center
Collaborating Sponsors:
Nitional institute of Health -National Center for Advancing Translational Sciences
Conditions:
Glioblastoma Multiforme
Glycolytic Index
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this project is to validate a new combined MRI and PET imaging technique as a biomarker or measure of glycolysis in brain tumors. To accomplish this, the investigators propose obtaining...
Detailed Description
Patients who are scheduled for resection of glioblastoma multiforme (GBM) as part of standard care will be invited to take part in the study. All patients will undergo FDG-PET scan for the study using...
Eligibility Criteria
Inclusion
- Age \> 18
- Patients with newly diagnosed or recurrent glioblastoma clinically indicated for resective surgery
Exclusion
- Patients who cannot obtain an MRI or FDG PET scan with contrast
- Those with ferromagnetic implanted devices that might produce a safety hazard (e.g. infusion pumps, pace makers, aneurysm clips, etc.) will be excluded from the study along with subjects with severe claustrophobia or who have severely compromised renal function (GFR \< 30).
Key Trial Info
Start Date :
September 6 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2028
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06059690
Start Date
September 6 2023
End Date
September 30 2028
Last Update
October 8 2025
Active Locations (1)
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1
University of California at Los Angeles
Los Angeles, California, United States, 90095-1406