Status:

UNKNOWN

Teriparatide on Maxillary Sinus Floor Osseointegration

Lead Sponsor:

Universidad de Valparaiso

Collaborating Sponsors:

Universidade Federal Fluminense

Conditions:

Bone Regeneration

Eligibility:

All Genders

25-70 years

Phase:

PHASE4

Brief Summary

The aim of this triple blind randomized controlled trial will be to analyze the effect of a dose of teriparatide combined with a xenograft on bone augmentation of the maxillary sinus, to observe the m...

Eligibility Criteria

Inclusion

  • Pneumatization of a maxillary sinus with a residual ridge ≤ 5 mm in height (according to baseline conebeam tomograph).
  • Must sign an informed consent to participate in this study.

Exclusion

  • Residual ridges less than 4 mm in height.
  • Uncontrolled systemic disease (ASA 3, 4, 5, and 6)
  • Presenting with osteoporosis or any disease of bone metabolism.
  • Having received radiotherapy.
  • Cancer.
  • Any systemic condition that affects calcium absorption.
  • Kidney disease.
  • Coagulation disorders.
  • History of sinusitis.
  • Maxillary sinus pathology.
  • Heavy smoking (\> 1 pack per day).
  • Drug or alcohol users.
  • Pregnancy.
  • Treatment with drugs that affect bone metabolism.
  • Treatment with immunosuppressants.
  • Allergies.
  • Uncontrolled periodontal pathology.
  • Tooth extractions in the last three months.

Key Trial Info

Start Date :

August 23 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT06061354

Start Date

August 23 2023

End Date

December 1 2024

Last Update

November 30 2023

Active Locations (1)

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Facultad de Odontología, Universidad de Valparaiso

Valparaíso, Región de Valparaíso, Chile, 2360004