Status:

COMPLETED

Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients

Lead Sponsor:

Ankara City Hospital Bilkent

Conditions:

Sepsis

Acetaminophen

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

This is a randomized double-blind controlled study with the primary aim of scientifically evaluating the potential effects of paracetamol and ibuprofen in the management of sepsis by comparing their f...

Detailed Description

This is a randomized double-blind controlled study with the primary aim of scientifically evaluating the potential effects of paracetamol and ibuprofen in the management of sepsis by comparing their f...

Eligibility Criteria

Inclusion

  • 18 years of age or older
  • Under 80 years of age
  • Willing to participate in the study
  • Diagnosed with sepsis according to the latest current guidelines
  • Having a fever \>38.3°C
  • With no known history of adverse reactions to the active ingredient of the medication to be used"

Exclusion

  • Under 18 years of age or over 80 years of age
  • Not willing to participate in the study
  • With a known history of adverse reactions to study medications
  • Having a fever \<38.3°C
  • Pregnant individuals
  • Individuals with advanced systemic illness
  • Those with malignancies
  • Patients with chronic liver and kidney disease
  • Using sedative and analgesic neuro-psychiatric drugs
  • With a history of psychological and neurological diseases"

Key Trial Info

Start Date :

October 31 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2024

Estimated Enrollment :

113 Patients enrolled

Trial Details

Trial ID

NCT06061575

Start Date

October 31 2023

End Date

December 1 2024

Last Update

February 4 2025

Active Locations (1)

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1

Ankara City Hospital

Ankara, Turkey (Türkiye), 06800