Status:

RECRUITING

Identification of Individual Histological and Blood Markers in Patients With Recurrent or Metastatic Upper Aerodigestive Tract Squamous Cell Carcinoma in Response to Immunotherapies

Lead Sponsor:

Fondation Hôpital Saint-Joseph

Conditions:

Squamous Cell Carcinoma of the Oropharynx

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Epidermoid Carcinoma of the Upper Aerodigestive Tract (CEVADS) is the 6th most common cancer worldwide. Despite current therapies (radiotherapy, surgery and chemotherapy), cancers of the Upper Aerodig...

Eligibility Criteria

Inclusion

  • Patients aged ≥ 18 years
  • Patients with histologically confirmed CEVADS involving the oral cavity, oropharynx, hypopharynx or larynx
  • Pre-treated patients with a first recurrence (locoregional or metastatic) who are candidates for immunotherapy
  • Patient affiliated to a health insurance plan
  • French-speaking patient
  • Patient with free, informed and written consent

Exclusion

  • Patients with a contraindication to immunotherapy (transplant patients)
  • Pregnant or breast-feeding patients
  • Patient under guardianship or curatorship
  • Patient under court protection
  • Patient deprived of liberty

Key Trial Info

Start Date :

January 29 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06061705

Start Date

January 29 2024

End Date

June 30 2026

Last Update

June 24 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Hôpital Saint-Joseph

Paris, France, 75014

2

Hôpital Bichat

Paris, France

3

Hôpital Saint-Louis

Paris, France