Status:

RECRUITING

Effect of Celery Seed on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion

Lead Sponsor:

University of Guadalajara

Conditions:

Metabolic Syndrome

Eligibility:

All Genders

30-60 years

Phase:

PHASE2

Brief Summary

The Metabolic Syndrome (MS) is a cluster of cardiometabolic risk factors, which include abdominal obesity, hyperglycemia, dyslipidemia, and high blood pressure. MS is a global health problem, it repre...

Detailed Description

A randomized, double-blind controlled clinical trial in 28 patients between 30 to 60 years of age with a diagnosis of MS according to the International Diabetes Federation (IDF) criteria without treat...

Eligibility Criteria

Inclusion

  • Patients both sexes
  • Age between 30 and 60 years
  • Diagnosis of metabolic syndrome (MS) according to the IDF criteria: waist circumference: ≥80 cm (women) ≥90 cm (men), plus two or more of the following:
  • Fasting glucose ≥ 100 mg/dL
  • Triglycerides ≥150 mg/dL
  • HDL-c: Men ≤40 mg/dL, women ≤50 mg/dL
  • Blood pressure ≥130/85 mmHg
  • Body Mass Index from 25 to 34.9 kg/m²
  • Stable weight at least the previous last 3 months (weight variation less than 10%)
  • No pharmacological treatment for MS, insulin sensitivity and insulin secretion
  • Acceptance and signing of informed consent

Exclusion

  • Pregnancy or breast-feeding
  • Glucose ≥126 mg/dL
  • Total cholesterol ≥240 mg/dL
  • Triglycerides ≥500mg/dL
  • Systolic blood pressure ≥140 mmHg
  • Diastolic blood pressure ≥90 mmHg
  • Drugs or supplements consumption with proven properties that modify the behavior of the study variables.
  • History of kidney, liver or thyroid disease

Key Trial Info

Start Date :

May 20 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT06061926

Start Date

May 20 2023

End Date

December 1 2025

Last Update

October 23 2024

Active Locations (1)

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INSTITUTO DE TERAPÉUTICA EXPERIMENTAL Y CLÍNICA. Centro Universitario de Ciencias de la Salud

Guadalajara, Jalisco, Mexico, 44340