Status:

RECRUITING

Benefit of Permanent Stimulation of the Left Branch of the His Bundle Versus Right Ventricular Stimulation After Atrioventricular Node Ablation for Rapid Atrial Fibrillation

Lead Sponsor:

University Hospital, Rouen

Conditions:

Atrial Fibrillation Rapid

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The objective of the study is to evaluate the functional benefit of left bundle branch of His pacing compared to right ventricular pacing in patients implanted with a pacemaker prior to a atrioventric...

Eligibility Criteria

Inclusion

  • 1/ Pacemaker implanted patient with LBTP lead and back-up right ventricular lead who subsequently underwent successful atrioventricular node ablation for rapid AF 2) NAV ablation procedure performed less than 15 days ago 3) Age ≥ 18 years 4) Woman of childbearing age with effective contraception (estrogen-progestin or intrauterine device or tubal ligation) for at least 1 month and for the duration of the study, and a negative urine pregnancy test by B-HCG at inclusion Or, Postmenopausal woman: confirmatory diagnosis (non-medically induced amenorrhea for at least 12 months prior to the inclusion visit).
  • 5\) Membership of a social security scheme 6) Patient follow-up feasible 7) Patient has read and understood the information leaflet and signed the informed consent form

Exclusion

  • Impairment of autonomy such that a maximal cardiorespiratory effort test (VO2 Max test) cannot be performed under good conditions (ADL scale \< 5).
  • LVEF \< 40% at inclusion
  • Person deprived of liberty by an administrative or judicial decision, or person under court protection, sub-guardianship or curatorship.
  • Patient participating in another interventional trial
  • Any history of illness or psychological or sensory abnormality likely to prevent the subject from fully understanding the conditions required for participation in the protocol, or from giving informed consent.
  • Pregnant, parturient or breast-feeding women, or those without proven contraception

Key Trial Info

Start Date :

November 27 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 27 2027

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06061978

Start Date

November 27 2023

End Date

May 27 2027

Last Update

December 5 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CHU de CAEN

Caen, France